
Faculty of Engineering
Junk DNA Diseases

Diseases, in genes that have lost function over thousands of years, are being encoded during the initial 3-4 days of the fetal development. Traces of diseases, which have been carried along over thousands of years in these DNA sequences, called as ‘Junk DNA’ by scientists, distinctively emerged for the first in the development of fetus. Assistant Professor Cihangir Yandım, Lecturer at Department of Genetics and Bioengineering, Izmir University of Economics (IUE), stated that scientists have overlooked this area; however, they established a new data for junk DNA research.
Yandım reported that he and Assoc. Prof. Gökhan Karakülah conducted a research in this area for the first time as part of an academic collaboration with Izmir University of Economics and Izmir Biomedicine and Genome Center, and their research was published in the journal of BMC Genomics; a Web of Science indexed high-impact journal. Yandım, who stated that the complete genome architecture was built within the first 3-4 days of a baby’s existence following the fertilization, said that junk codes that have lost function over thousands of years were also being transferred within this structure.
‘Meaningful codes stay afloat on water’
Yandım, who indicated that research of junk DNA would be very effective in uncovering the mystery of humanity and generating organs in a lab setting, stated the following about his research:
“A fertilized egg first gives rise to 2 cells with division, followed by 4,8,16 and 64 cells respectively. A 64-cell human embryo resembles a sphere. Some of these cells would later form brain or lungs, liver or other organs through division in the subsequent stages. There is no doubt that genes have a high level of importance in establishing genetic expression patterns. However, our genomic architecture does not solely comprise meaningful islets called “genes”. If the whole human DNA would be considered as the Pacific Ocean, meaningful codes called as “genes” would only represent those little islets we see on top of the water.”
‘Most of the human DNA is formed by the junk in the DNA’
Yandım reported that genes that became evolutionarily redundant over thousands of years and ancient virus DNAs were transferred into this ocean called as “junk” by scientists, and maintained their presence along with functional genes. Yandım, who stated that most of the human DNA was formed by this underwater junk, added the following: “In our study, we investigated the activity of junk DNA pieces during human embryonic development for the first time. China is the only country allowing experimental studies with human embryos. In our study based on the data published by China, we surprisingly found out that these codes are essential factors maintaining our genetic structure and contributing to the development of the human embryo for the first time. It will be highly impactful to perform further research on this junk DNA, which is often overlooked in modern medicine, in terms of revealing the secrets of human DNA and generating organs in the laboratory environment or treating diseases.”
NEWS |ALL NEWS

OCCUPATIONAL HEALTH AND SAFETY TRAINING
Within the scope of BME 318 course, an Occupational Health and Safety Seminar was given to Biomedical Engineering students by our University's

ECO-Dynamics places second in Teknofest Helicopter Design Competition with their attack helicopter
The "ECO-Dynamics" team, consisting of 7 students, Pınar Akın, Eda Nur Tetik, Kutlu Akar, Melisa Gündoğdu, Mehmet Ali Tekin, Tuna Deniz ve

They came second with the helicopter design
The ‘ECO-Dynamics’ team, consisting of 7 students from Izmir University of Economics (IUE) Department of Aerospace Engineering,

Visitor from NASA
Jay Trimble, Mission System Manager at NASA Ames Research Center, met with students at the two-day conference on NASA's Space Travel, organized

We should take advantage of industrial building technology
Building tests and urban transformation works gained momentum throughout Turkey after the earthquake disaster, the epicenter of which was Kahramanmaraş and killed

Vital warnings in building inspections
After the earthquake disaster, the epicenter of which was Kahramanmaraş and which caused destruction in 10 cities, thousands of citizens rushed to

Negligence, not the soil, demolishes
Prof. Dr. Celalettin Kozanoğlu, Head of Department of Civil Engineering, Izmir University of Economics (IUE), stated that many buildings that were destroyed

Exemplary collaboration for high school students
Izmir University of Economics (IUE) signed a protocol with Izmir Girls' High School by adding a new one to its collaborations to